Shalom Life | April 15, 2015

Israelis Discover New Proteins That Can Suppress Cancer

A team of Israeli researchers have recently discovered two proteins that can help suppress and control the growth and development of cancer

By: Caitlin Marceau

Published: April 14th, 2015 in Health » Israel

Photo: Protein fending off aging-related cellular damage

Credit: Top News


Two cancer suppressing proteins, that can also control the cell’s growth and development, have been discovered by a team of Israeli researchers. The group include Nobel-prize winner Professor Aaron Ciechanover, and a team led by Dr. Yelena Kravtsova-Ivantsiv at the Technion, and included researchers and physicians from the Rambam, Carmel, and Hadassah Medical Centers.

The study, which was conducted on human tumours grown on mice and samples of other human tumours, was published in Cell, a scientific journal, just last week. The paper explained how proteins called KPC1 and p50, when in tissue, can help protect it from cancerous tumours.

Their report also explained how these two proteins could help repress cancerous tissues from forming.

The team also discovered how the ubiquitin process, which is a cell system that breaks down damaged proteins but can also harm other cells and tissues, which Ciechanover won his Nobel-prize for co-discovering, was also proven to have a function in helping control and suppress cancerous cells.

According to Ciechanover, as quoted by The Times of Israel, years more of research and observation are needed in order, “to establish the research and gain a solid understanding of the mechanisms behind the suppression of the tumors. The development of a drug based on this discovery is a possibility, although not a certainty, and the road to such a drug is long and far from simple.”

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