Shalom Life | September 01, 2014

Has the Fountain of Youth Been Discovered in Israel?

Israeli university researchers unveil their discovery of a gene that increases the lifespan of lab animals, and perhaps of humans too.

By: Abigail Klein Leichman

Published: February 28th, 2012 in Health » Israel

Has the Fountain of Youth Been Discovered in Israel?

All the anti-aging potions, lotions and notions on the market and in development add up to a very pretty penny. Maybe some of them actually work. Yet the biology behind aging, and how to slow its effects, has never been well understood.

Now, seven years of Israeli research have revealed that it may all come down to a specific gene called Sirtuin 6, or SIRT6 for short. They described their study in the February 22 online issue of the popular science journal Nature.

SIRT6 is one of seven sirtuin genes that encode a class of proteins found in every species from single-celled yeast to complex humans. For years, scientists had zeroed in on SIRT1. When they removed SIRT1 from yeast, worms and flies, these creatures aged faster and died sooner. When they transplanted a copy of SIRT1 into the three species instead, their life expectancy increased.

But yeast and flies aren't mammals. So molecular biologist Haim Cohen of Bar-Ilan University instead turned his attention to a 2006 study involving SIRT6, which showed that mice lacking this gene aged more quickly, developing spinal curvature, calcium deficiency, osteoporosis, immune system problems and diabetes -- just like humans.

"People were mostly interested in SIRT1," Cohen said. "So I thought it might be better for us as a new lab to work on something that is less crowded."

His Bar-Ilan graduate student Yariv Kanfi spent more than five years breeding mice that would receive an extra dose of SIRT6. Most of the lab work was done in Bar-Ilan, the pathology at Hebrew University's Hadassah Medical School and the bioinformatics by Ziv Bar-Joseph, an Israeli professor at Pennsylvania's Carnegie Mellon University.

This article is republished with permission from Israel21c. To read the rest of the story, click here.

Israeli Company Hopes to Find Real Treatment for ALS Israeli Company Hopes to Find Real Treatment for ALS TrendingWhey Good News for Diabetics Whey Good News for Diabetics TrendingStudy: An Overwhelming 86% of Israelis Are Happy, Despite the Conflict Study: An Overwhelming 86% of Israelis Are Happy, Despite the Conflict Trending
 

Lea Michele to Join Season 4 of ‘American Horror Story’?

September 01, 2014 | By Ashley Baylen
Lea Michele to Join Season 4 of ‘American Horror Story’?

The 'Glee' actress is rumored to join 'American Horror Story: Freak Show'.

Read More

Melissa Rivers is “Keeping Fingers Crossed” For Joan’s Recovery

September 01, 2014 | By Ashley Baylen
Melissa Rivers is “Keeping Fingers Crossed” For Joan’s Recovery

The 81-year-old comedian has been in a medically induced coma since Friday.

Read More

Lena Dunham: Leaking Nude Photos is a Sex Offense

September 01, 2014 | By Ashley Baylen
Lena Dunham: Leaking Nude Photos is a Sex Offense

The 'Girls' creator urges her fans not to look at the recently leaked nude photos of fellow celebrities.

Read More

Jewish ‘Hoops Whisperer’ A Secret Weapon For NBA Stars

September 01, 2014 | By Robert Gluck
Jewish ‘Hoops Whisperer’ A Secret Weapon For NBA Stars

Idan Ravin's new book, "The Hoops Whisperer: On the Court and Inside the Head of Basketball's Best Players," details his rise from a Jewish upbringing to becoming a well-respected figure in NBA circles

Read More

Israeli Company Hopes to Find Real Treatment for ALS

September 01, 2014 | By Maya Yarowsky and Anouk Lorie, NoCamels
Israeli Company Hopes to Find Real Treatment for ALS

BrainStorm looks beyond the Ice Bucket Challenge to treat Lou Gehrig's Disease with their NurOwn treatment

Read More

An Amulet a Son Gave to His Mother During the Holocaust Has Been Uncovered

September 01, 2014 | By Itamar Aichner, Yedioth Aharonot
An Amulet a Son Gave to His Mother During the Holocaust Has Been Uncovered

Unearthed in the ruins of the Lodz ghetto, the amulet reads 'With love, Avram'

Read More

What You Missed in the News: August 25 - September 1

September 01, 2014 | By Daniel Koren
What You Missed in the News: August 25 - September 1

Our Top Stories this week SodaStream, Howard Stern, Curb Your Enthusiasm, ReWalk, Shoes by Jews, and more

Read More

The Ten Best Curb Your Enthusiasm Episodes

August 29, 2014 | By Caitlin Marceau & Daniel Koren
The Ten Best Curb Your Enthusiasm Episodes

While Season 9 may be a mere fallacy, we do have 8 seasons of Larry David's hilariously awkward comedy to keep us company

Read More

More Headlines