Shalom Life | December 22, 2014

Israeli 'Wrapping Paper' Allows Your Bones to Heal More Efficiently

Israeli company Regenecure is developing an intelligent wrapping paper that will allow broken bones to heal faster, and more smoothly

By: Johanna Weiß

Published: December 17th, 2013 in Health » Israel

Israeli 'Wrapping Paper' Allows Your Bones to Heal More Efficiently

“Break a leg” may be what people say when they want to wish someone luck, but breaking a leg is more than bad luck. That is especially true for elderly people, who’s weaker bones often lead to severe fractures and complications.

Thanks to the Israeli company Regenecure, that may no longer be the case. Regenecure is developing what can be understood as an intelligent wrapping paper that enables broken bones to heal faster, more smoothly and even compensate bone loss.

In medical terminology, this wrapping paper is called membrane implant. “Membranes in general are semi-selective materials. They allow certain materials to get through, while others cannot,” CEO Moshe Tzabari tells NoCamels.

When the Regenecure membrane is wrapped around the broken bone, it allows fluids to get through, but prevents cells, vigor or soft tissue from getting to the bone. This feature is crucial for the healing process.

“After a fracture there is a competition going on in the human body between soft tissue and bone,” Tzabari explains. “If there is no barrier, soft tissue will infiltrate the wound and stop the bone from growing or make it grow in unintended ways.”

The membrane implant is a transparent, thin-yet-strong material that looks like plastic wrap. However, the membrane is regenerative and can be sutured, drilled and shaped into any geometrical form. Moreover, it attracts stem cells to grow and populate along the membrane surface.

The material, which comes from Germany, has been used in the past as a drug delivery system – to cover tablets that are not meant to dissolve in the stomach but only to take effect later. Michael Friedman, Professor at the Hebrew University in Jerusalem, discovered that the same material can be used to enable guided bone growth after fractures. The membrane implant can assist, and sometimes replace, traditional healing methods, he explains.

Cutting healing time in half

Comparative research has been done with sheep that suffered from fractures with high bone loss. Treated with splints only, these fractures never healed. With an additional bone-graft substitute, it took bones 28 weeks to heal. When using the membrane implant instead of the bone-graft, it also took 28 weeks, but Regencure says the growth proved to be more complete. Finally, when the membrane implant was combined with bone-graft substitute, complete healing took only 8-14 weeks.

“In short, the membrane implant can replace bone-graft substitute for better healing or even halve the time of healing if used in combination with bone craft substitute,” Tzabari says.

While Regenecure was only ever meant to be used in humans, when vets heard about the membrane implant, they wanted in as well. In June of this year, vets started using the product in dogs and sheep, as licensing requirements on the veterinary market are lower than in human medicine.

A future in cranial reconstruction

Tzabari used to be a consultant for medical products before he joint Regenecure. He sees the future of fracture treatment in the combination of membrane implant with traditional approaches. According to him, the market is in the billion dollar range. “This is not only less painful for the patient, it also makes sense from an economical point of view. A second operation after fractures to harvest bone costs between $2,000 and $3,000. Our implant will be sold for $800.”

Regenecure’s first product for human medicine will be in the dental market at the end of 2014. The membrane implant will enable bone growth that is needed for teeth implants. The European Market will be approached first. Once the product receives the European CE mark of approval, it will also be allowed in most countries outside the European Union. The US market will probably be entered last after gaining FDA approval. Regenecure will look to enter the market of human fractures in mid-2015.

In an even more distant future, Tzabari hopes the implant might even be used in cranial medicine for example, to reconstruct face bones after serious accidents. The company is currently in the trial period for this use.

This article published on No Camels - Israeli Innovation News

Israeli Study: Kids Start Enjoying the Misfortune of Others At Very Early Age Israeli Study: Kids Start Enjoying the Misfortune of Others At Very Early Age TrendingIsraeli Researchers: We're Most Likely Alone in the Universe Israeli Researchers: We're Most Likely Alone in the Universe TrendingIsrael Hailed As A World Leader in Medical Tourism Israel Hailed As A World Leader in Medical Tourism Trending
 

Top 50 Hottest Jewish Women of 2014 (30-21)

December 19, 2014 | By Ashley Baylen
Top 50 Hottest Jewish Women of 2014 (30-21)

Join Shalom Life in celebrating the 50 most talented, intelligent, funny, and beautiful Jewish women of the year.

Read More

Analyst Suggests Qatar 'Give' World Cup 2022 to Gaza

December 19, 2014 | By Daniel Koren
Analyst Suggests Qatar 'Give' World Cup 2022 to Gaza

Tom Gross argues that the move would be beneficial for Palestinians in Israel

Read More

Natalie Portman Explains How 'Star Wars' Almost Ruined Her Career

December 19, 2014 | By Sara Torvik
Natalie Portman Explains How 'Star Wars' Almost Ruined Her Career

The 'Black Swan' actress says no one wanted to work with her after 'Star Wars'

Read More

Liberace's Hologram to Go On World Tour, Starting in Las Vegas

December 19, 2014 | By Sara Torvik
Liberace's Hologram to Go On World Tour, Starting in Las Vegas

The deceased performer will be entertaining a whole new generation of fans.

Read More

Adam Levine's Maroon 5 Rock Out at The People Magazine Awards [VIDEO]

December 19, 2014 | By Sara Torvik
Adam Levine's Maroon 5 Rock Out at The People Magazine Awards [VIDEO]

On Thursday evening, Maroon 5 wowed the audience with a live performance of 'Animals'

Read More

Oops! Drake Confused Adam Silver for Donald Sterling

December 19, 2014 | By Sara Torvik
Oops! Drake Confused Adam Silver for Donald Sterling

At the Toronto Raptors Drake night, Drake mixed up some important names.

Read More

Ambassador Dan Shapiro Urges U.S. Collaboration with Jerusalem College of Technology

December 19, 2014 | By ShalomLife Team
Ambassador Dan Shapiro Urges U.S. Collaboration with Jerusalem College of Technology

Shapiro visited the college for a private demonstration of several ground-breaking technologies developed by students

Read More

This British Politician Is Trying to Put an End to Racism & anti-Semitism on Twitter

December 19, 2014 | By Daniel Koren
This British Politician Is Trying to Put an End to Racism & anti-Semitism on Twitter

Luciana Berger, the subject of some 2,500 anti-Semitic tweets earlier this year, wants the platform to ban racist words

Read More

More Headlines